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Burkholderia cepacia complex Infections Associated with Use of Medline Remedy Essentials No-Rinse Foam

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Burkholderia cepacia complex Infections Associated with Use of Medline Remedy Essentials No-Rinse Foam

CDC is providing support to state and local health departments in the investigation of two clusters of Burkholderia cepacia complex (Bcc) infections at two acute care hospitals in Pennsylvania and California. Infections occurred between November 2017 and March 2018. As of March 23, 2018, five of the ten patients from the Pennsylvania cluster and six of the eight patients from the California cluster have had Bcc isolated from urine. Other body sites positive for Bcc included wounds and sputum.

The ongoing investigation has identified a potential association between Bcc infection and Medline Remedy Essentials No-Rinse Foam, a product used for skin and perineal care in both facilities. Samples of the product were collected at the Pennsylvania facility from lots M05703/7235 and M06691/7256, which tested positive for Bcc. However, it is not known which lots were used on the patients who developed infections. Molecular testing on clinical and product isolates indicate that they are closely related. Cultures from additional product are pending.

Facilities should consider avoiding the use of this product, at least in patients at greater risk for Bcc infection, until further information is available. To report similar clusters of Bcc with a majority of patients having positive urine cultures occurring since 2/1/2018 among non-cystic fibrosis patients to CDPHE, or for additional information, please contact Geoff Brousseau at 303-692-2766 or geoffrey.brousseau@state.co.us.


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